(Photo credit: Isaiah J. Downing-Imagn Images)

Daulton Varsho homered twice, doubled and drove in a career-best six runs as the Toronto Blue Jays beat the Colorado Rockies 10-4 in Denver on Tuesday night.

Vladimir Guerrero homered among his three hits, Nathan Lukes and Addison Barger also went deep for Toronto, which will shoot for a three-game series sweep on Wednesday. Lukes, Bo Bichette and Alejandro Kirk had two hits each.

Hunter Goodman homered and singled for the Rockies, who have lost three in a row.

Both teams had players exit the game with injuries.

Colorado lost third baseman Orlando Arcia in the fifth inning when he hurt his right arm on a single to right, and second baseman Thairo Estrada left at the end of the sixth with a right leg injury sustained running to first base on a double play.

Blue Jays left fielder Joey Loperfido came out in the sixth inning after he was hit outside his right knee by a 98 mph fastball from Colorado reliever Angel Chivilli.

Goodman gave the Rockies the lead with a two-run homer in the first, but Lukes hit a solo home run in the third and Varsho's first homer of the night, a two-run shot to right field, gave Toronto a 3-2 lead in the fourth.

The Blue Jays continued their power surge in the sixth inning. Guerrero and Bargas homered on consecutive pitches. Kirk walked and Varsho hit a 3-2 changeup off the facing of the third deck in right field for a 7-2 lead.

His 11th home run of the season was measured at 467 feet. Through the first two games of the series, Varsho is 5-for-10 with three homers and 10 RBIs.

Rockies right-hander Anthony Molina (0-1), who made his first major league start of the season, allowed nine runs on seven hits over five-plus innings. He walked one and struck out two.

Colorado got two runs back in the bottom of the sixth. Goodman singled, and Toronto starter Jose Berrios hit Jordan Beck with a pitch. Mickey Moniak singled to right, and Goodman scored when Varsho bobbled the ball. Warming Bernabel followed with an RBI single to make it 7-4.

Berrios (8-4) allowed four runs -- three earned -- on seven hits and one walk over 5 1/3 innings. He fanned five.

Toronto boosted the margin in the ninth on Guerrero's RBI double and Varsho's two-run double.

--Field Level Media